Which building remains from the 1893 World's Fair?

The Museum of Science and Industry is the correct answer because it is housed in the only remaining building from the 1893 World's Columbian Exposition, which was held in Chicago. Originally built as the Palace of Fine Arts for the fair, this structure showcases Beaux-Arts architectural style, and after the fair, it was repurposed and transformed into the museum it is today.

The Chicago Cultural Center and the Art Institute of Chicago, while significant in their own right, were not constructed for the 1893 fair and represent different periods and styles within Chicago's rich architectural history. Similarly, the Shedd Aquarium, although also built in the early 20th century, was constructed after the fair and is not linked to the 1893 event's buildings. Thus, the Museum of Science and Industry uniquely stands as a direct relic of the World's Fair.